Focus Wound Healing
Aposcience AG has found that the mixture of active components secreted from cultured apoptotic peripheral white blood cells (lipids, exosomes, and proteins) has superior efficacy in promoting wound healing and skin regeneration. The products have this effect by stimulating migration of keratinocytes and fibroblasts into the wounded area, as well as by promoting neovascularization of the wound and improving blood and oxygen supply.
The company expects that the secretome derived from stressed PBMCs will have a significant impact in the care for millions of patients who are afflicted by poorly healing wounds (diabetic foot ulcers, ischemic ulcerations, pressure ulcers) and therefore present a very important market opportunity.
Currently, a multinational, double-blind randomized clinical trial (MARSYAS II) is conducted.